3-(4-溴-3-甲基苯基)-5-甲基-1,2,4-噁二唑合成路线 (共 4 条)
反应条件
1: 90 percent / NH2OH / methanol View Scheme
参考文献
Wyman, Paul A.; Marshall, Howard R.; Flynn, Sean T.; King, Ron J.; Thompson, Mervyn; Smith, Paul W.; Hadley, Michael S.; Price, Gary W.; Scott, Claire M.; Dawson, Lee A.
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 21 p. 4708 - 4712
参考文献
Wyman, Paul A.; Marshall, Howard R.; Flynn, Sean T.; King, Ron J.; Thompson, Mervyn; Smith, Paul W.; Hadley, Michael S.; Price, Gary W.; Scott, Claire M.; Dawson, Lee A.
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 21 p. 4708 - 4712
反应条件
tetrakis(triphenylphosphine) palladium(0); sodium carbonate in ethylene glycol dimethyl ether; water
参考文献
Clitherow; Scopes; Skingle; Jordan; Feniuk; Campbell; Carter; Collington; Connor; Higgins; Beattie; Kelly; Mitchell; Oxford; Wadsworth; Tyers
Journal of Medicinal Chemistry, 1994 , vol. 37, # 15 p. 2253 - 2257
反应条件
tetrakis(triphenylphosphine) palladium(0); sodium carbonate in water; N,N-dimethyl-formamide Substitution; 24 h; Heating;
参考文献
Liao, Yi; Boettcher, Henning; Harting, Juergen; Greiner, Hartmut; Van Amsterdam, Christoph; Cremers, Thomas; Sundell, Staffan; Maerz, Joachim; Rautenberg, Wilfried; Wikstroem, Hakan
Journal of Medicinal Chemistry, 2000 , vol. 43, # 3 p. 517 - 525