3-溴-2-氧代戊二酸 二甲酯合成路线 （共 6 条）
反应条件
copper(ll) bromide in chloroform; ethyl acetate 18 h; Heating;
参考文献
CHEMIZON, A DIVISION OF OPTOMAGIC CO., LTD.
Patent: US2012/238599 A1, 2012 ;
Location in patent: Page/Page column 32 ;
US 20120238599 A1
反应条件
1: 81 percent / 2,2-Dimethoxypropan / 144 h / Ambient temperature 2: 85 percent / Br2 / CCl4 / Heating; Irradiation View Scheme
参考文献
Hartenstein, H.; Blitzke, T.; Sicker, D.; Wilde, H.
Journal fuer Praktische Chemie/Chemiker-Zeitung, 1993 , vol. 335, # 2 p. 176 - 180
反应条件
1: Et3N / diethyl ether / 20 h / 25 °C 2: CH2Cl2 / 7 h / 25 °C 3: dry hydrogen chloride / CH2Cl2 / 10 h 4: 60 percent / ceric ammonium nitrate / acetonitrile; H2O / 0.17 h / 0 °C 5: 92 percent / p-tuluenesulfonic acid / methanol / 4 h / Heating 6: 98 percent / 0.5 M K2CO3 / H2O / 4 h / 85 °C View Scheme
参考文献
Journal of the American Chemical Society, , vol. 103, p. 5599
反应条件
1: Et3N / diethyl ether / 20 h / 25 °C
2: CH2Cl2 / 7 h / 25 °C
3: dry hydrogen chloride / CH2Cl2 / 10 h
4: 60 percent / ceric ammonium nitrate / acetonitrile; H2O / 0.17 h / 0 °C
5: 92 percent / p-tuluenesulfonic acid / methanol / 4 h / Heating
6: 98 percent / 0.5 M K2CO3 / H2O / 4 h / 85 °C
7: NH4OH / H2O / 30 h / 23 °C
View Scheme
参考文献
Corey,E.J.; Tramontano,A.
Journal of the American Chemical Society, 1981 , vol. 103, p. 5599
反应条件
1: Et3N / diethyl ether / 20 h / 25 °C
2: CH2Cl2 / 7 h / 25 °C
3: dry hydrogen chloride / CH2Cl2 / 10 h
4: 60 percent / ceric ammonium nitrate / acetonitrile; H2O / 0.17 h / 0 °C
View Scheme
参考文献
Corey,E.J.; Tramontano,A.
Journal of the American Chemical Society, 1981 , vol. 103, p. 5599
反应条件
triethylamine in diethyl ether
T=25°C; 20 h; Yield given;
参考文献
Corey,E.J.; Tramontano,A.
Journal of the American Chemical Society, 1981 , vol. 103, p. 5599
