1: 7-nitrogramine With water; methyl iodide in tetrahydrofuran; N,N-dimethyl-formamide 0.25 h; Heating / reflux; 2: potassium cyanide in tetrahydrofuran; water; N,N-dimethyl-formamide 2 h; Heating / reflux;

in tetrahydrofuran; water; N,N-dimethyl-formamide 2 h; Heating / reflux;

1: 7-nitrogramine; methyl iodide in tetrahydrofuran; water; N,N-dimethyl-formamide 0.25 h; Reflux; 2: potassium cyanide 2 h; Reflux;

1.1: water / 72 h / 20 °C 2.1: N,N-dimethyl-formamide; water; tetrahydrofuran / 0.25 h / Reflux 2.2: 2 h / Reflux View Scheme