(S)-2-(2-溴苯基)-4-异丙基-4,5-二氢噁唑合成路线 （共 8 条）
反应条件
zinc(II) chloride in chlorobenzene 24 h; Heating;
参考文献
Zhou, Qi-Lin; Pfaltz, Andreas
Tetrahedron, 1994 , vol. 50, # 15 p. 4467 - 4478
反应条件
pyridine; triethylamine; triphenylphosphine in tetrachloromethane; acetonitrile 24 h;
参考文献
Peer, Markus; De Jong, Johannes C.; Kiefer, Matthias; Langer, Thomas; Rieck, Heiko; Schell, Heico; Sennhenn, Peter; Sprinz, Juergen; Steinhagen, Henning; Wiese, Burkhard; Helmchen, Guenter
Tetrahedron, 1996 , vol. 52, # 21 p. 7547 - 7583
反应条件
1: in toluene T=20°C; 24 h; Molecular sieve; 2: With potassium phosphate; N-bromosuccinmide in toluene T=20°C; 3.08333 h;
参考文献
Binda, Pascal I.; Abbina, Srinivas; Du, Guodong
Synthesis, 2011 , # 16 art. no. M40611SS, p. 2609 - 2618
反应条件
1: triethylamine / 0 - 20 °C 2: triethylamine / 0 - 20 °C 3: sodium hydroxide / methanol; water / 4 h / Reflux View Scheme
参考文献
Jin, Yu; Du, Da-Ming
Tetrahedron, 2012 , vol. 68, # 18 p. 3633 - 3640
反应条件
1: thionyl chloride / 4 h / 80 °C 2: triethylamine / 0 - 20 °C 3: triethylamine / 0 - 20 °C 4: sodium hydroxide / methanol; water / 4 h / Reflux View Scheme
参考文献
Jin, Yu; Du, Da-Ming
Tetrahedron, 2012 , vol. 68, # 18 p. 3633 - 3640
反应条件
magnesium; ethylene dibromide Heating;
参考文献
Peer, Markus; De Jong, Johannes C.; Kiefer, Matthias; Langer, Thomas; Rieck, Heiko; Schell, Heico; Sennhenn, Peter; Sprinz, Juergen; Steinhagen, Henning; Wiese, Burkhard; Helmchen, Guenter
Tetrahedron, 1996 , vol. 52, # 21 p. 7547 - 7583
反应条件
n-butyllithium in diethyl ether; hexane
T=-78°C; 1 h;
参考文献
Cmoch, Piotr; Urbanczyk-Lipkowska, Zofia; Petrosyan, Armine; Stepien, Anita; Stalinski, Krzysztof
Journal of Molecular Structure, 2005 , vol. 733, # 1-3 p. 29 - 39
反应条件
iodine; magnesium
1.) THF, RT, 10 h, 2.) THF, reflux, 5 h; Yield given. Multistep reaction;
参考文献
Peer, Markus; De Jong, Johannes C.; Kiefer, Matthias; Langer, Thomas; Rieck, Heiko; Schell, Heico; Sennhenn, Peter; Sprinz, Juergen; Steinhagen, Henning; Wiese, Burkhard; Helmchen, Guenter
Tetrahedron, 1996 , vol. 52, # 21 p. 7547 - 7583
