苯基(1-甲基丙基)硫醚合成路线 （共 33 条）
反应条件
1: 1.) n-BuLi / 1.) THF, -23 deg C, 20 min, 2.) -23 deg C, 0.5 h
2: sec-BuLi, TMEDA / 1.) THF, cyclohexane, -45 deg C, 1 h, 2.) 45 min
3: 89.7 percent / sec-BuLi / tetrahydrofuran; cyclohexane / 1 h / -45 °C
View Scheme
参考文献
Cohen,T.; Ritter,R.H.; Oulette,D.
Journal of the American Chemical Society, 1982 , vol. 104, p. 7142
反应条件
in tetrahydrofuran
T=-85 - -45°C;
参考文献
Harada, Toshiro; Maeda, Hisatomo; Oku, Akira
Tetrahedron Letters, 1985 , vol. 26, # 52 p. 6489 - 6492
反应条件
water in diethyl ether
T=-78 - 0°C; 1.) -78 deg C, 0.5 h, 2.) -50 deg C, 2.5 h, 3.) 0 deg C, 5 h, 4.) H2O;
参考文献
Cohen, Theodore; Yu, Lin-Chen
Journal of Organic Chemistry, 1984 , vol. 49, # 4 p. 605 - 608
参考文献
Taylor
Journal of the American Chemical Society, 1936 , vol. 58, p. 2649,2650
参考文献
Taylor
Journal of the American Chemical Society, 1936 , vol. 58, p. 2649,2650
反应条件
zinc; {2,6-(Ph2PO)2-C6H3}NiCl in N,N-dimethyl-formamide
4 h; Heating;
参考文献
Gomez-Benitez, Valente; Baldovino-Pantaleon, Oscar; Herrera-Alvarez, Cesar; Toscano, Ruben A.; Morales-Morales, David
Tetrahedron Letters, 2006 , vol. 47, # 29 p. 5059 - 5062
反应条件
potassium carbonate in acetone
24 h; Reflux;
参考文献
Mattiza, Jens T.; Meyer, Vera J.; Duddeck, Helmut
Magnetic Resonance in Chemistry, 2010 , vol. 48, # 3 p. 192 - 197
反应条件
KC8 in tetrahydrofuran
1 h; Ambient temperatureorder of cleavage, cleavage ratio; Product distribution;
参考文献
Beak, Peter; Sullivan, Thomas A.
Journal of the American Chemical Society, 1982 , vol. 104, # 16 p. 4450 - 4457
反应条件
quinine powder in benzene
5 h; Heating;
参考文献
Julia, S.; Ginebreda, A.; Guixer, J.; Tomas, A.
Tetrahedron Letters, 1980 , vol. 21, p. 3709 - 3712
反应条件
1: NaOMe
2: KOtBu
3: KOtBu
4: H2 / Raney-Ni
View Scheme
参考文献
Parham,W.E. et al.
Bulletin of the Chemical Society of Japan, 1972 , vol. 45, p. 509 - 515
