螺[1,3-二氧戊环-2,7'-双环[2.2.1]庚-2-烯]合成路线 （共 3 条）
反应条件
toluene-4-sulfonic acid in benzene 4 h; Heating;
参考文献
Fujita, Toshiaki; Tanaka, Masakazu; Norimine, Yoshihiko; Suemune, Hiroshi; Sakai, Kiyoshi
Journal of Organic Chemistry, 1997 , vol. 62, # 12 p. 3824 - 3830
反应条件
1.1: phenyl-magnesium bromide / diethyl ether / Reflux 2.1: oxalyl dichloride; dimethyl sulfoxide / dichloromethane / -78 °C 2.2: 0.5 h / -78 - 20 °C 3.1: toluene-4-sulfonic acid / benzene / 4 h / Reflux View Scheme
参考文献
BRISTOL-MYERS SQUIBB COMPANY; BELEMA, Makonen; SRINIVASU, Pothukanuri; BENDER, John A.; LOPEZ, Omar D.; CHEN, Qi; RAMPULLA, Richard A.; GUPTA, Samayamunthula Venkata Satya Arun Kumar; MEANWELL, Nicholas A.
Patent: WO2012/21591 A1, 2012 ;
WO 2012/021591 A1
反应条件
1: CCl4
2: (thermolysis)
View Scheme
参考文献
Gassman,P.G.; Schaffhausen,J.G.
Journal of Organic Chemistry, 1978 , vol. 43, p. 3214 - 3223
