N-乙酰-L-亮氨酸甲酯合成路线 （共 24 条）
反应条件
{(1,5-cyclooctadiene)Rh(1,2-bis((2S,5S)-2,5-diethylphospholano)benzene)}triflate; hydrogen in methanol T=20 - 25°C; P=1551.4 Torr;
参考文献
Burk, Mark J.
Journal of the American Chemical Society, 1991 , vol. 113, # 22 p. 8518 - 8519
反应条件
hydrogen; [Rh(NBD)((R)-Prophos)]ClO4 in methanol P=2585.7 Torr; Ambient temperature; Title compound not separated from byproducts;
参考文献
Journal of Organic Chemistry, , vol. 46, p. 5086 - 5093
反应条件
hydrogenchloride in dichloromethane T=0°C; 0.333333 h;
参考文献
Garcia, Jordi; Gonzalez, Javier; Segura, Ramon; Vilarrasa, Jaume
Tetrahedron, 1984 , vol. 40, # 16 p. 3121 - 3128
反应条件
hydrogen; [(R,R-DIPAMP)Rh(COD)]BF4 in methanol P=2585.7 Torr; Ambient temperature; Title compound not separated from byproducts;
参考文献
Journal of Organic Chemistry, , vol. 46, p. 5086 - 5093
反应条件
in dichloromethane T=20°C; 4 h;
参考文献
De Marco, Rosaria; Gioia, Maria Luisa Di; Leggio, Antonella; Liguori, Angelo; Viscomi, Maria Caterina
European Journal of Organic Chemistry, 2009 , # 22 p. 3795 - 3800
反应条件
potassium carbonate in N,N-dimethyl-formamide
参考文献
Rella, Maria Rosaria; Williard, Paul G.
Journal of Organic Chemistry, 2007 , vol. 72, # 2 p. 525 - 531
反应条件
1: POCl3 / toluene / 16 h / Heating 2: KI / acetone / 3 h / Heating 3: Zn, MeOH / 20 °C 4: H2 / (S,S)-bppm, (bicyclo<2.2.1>hepta-2,5-diene)chlororhodium(I) dimer / methanol / 2585.7 Torr / Ambient temperature View Scheme
参考文献
Journal of Organic Chemistry, , vol. 46, p. 5086 - 5093
反应条件
in hexane; isopropyl alcohol T=40°C;
参考文献
Journal of the American Chemical Society, , vol. 102, # 23 p. 7122 - 7123
反应条件
1: KI / acetone / 3 h / Heating 2: Zn, MeOH / 20 °C 3: H2 / (S,S)-bppm, (bicyclo<2.2.1>hepta-2,5-diene)chlororhodium(I) dimer / methanol / 2585.7 Torr / Ambient temperature View Scheme
参考文献
Journal of Organic Chemistry, , vol. 46, p. 5086 - 5093
反应条件
1: KI / acetone / 3 h / Heating 2: Zn, MeOH / 20 °C 3: H2 / (2S,3S)-bis(diphenylphosphino)butane <(S,S>-chiraphos> - rhodium norbornadiene perchlorate - complex / methanol / 2585.7 Torr / Ambient temperature View Scheme
参考文献
Journal of Organic Chemistry, , vol. 46, p. 5086 - 5093
