O-[(4-甲基苯基)磺酰基]-N-[苄氧羰基]-L-丝氨酸甲酯合成路线 （共 9 条）
参考文献
Journal of the American Chemical Society, , vol. 85, p. 1123 - 1126
反应条件
1: 99 percent / SOCl2 2: pyridine View Scheme
参考文献
Tetrahedron Letters, , vol. 44, # 28 p. 5251 - 5253
反应条件
1: 78 percent / NaHCO3 / toluene; H2O 2: 99 percent / SOCl2 3: pyridine View Scheme
参考文献
Tetrahedron Letters, , vol. 44, # 28 p. 5251 - 5253
反应条件
1: KI / acetone View Scheme
参考文献
Maerki; Schwyzer
Helvetica chimica acta, 1975 , vol. 58, # 5 p. 1471 - 1477
反应条件
potassium carbonate; tetra-(n-butyl)-phosphonium bromide in toluene
T=25°C; 24 - 192 h;
参考文献
F. HOFFMANN-LA ROCHE AG
Patent: EP1236715 A2, 2002 ;
Location in patent: Example 9; 10 ;
参考文献
F. Hoffmann-La Roche AG
Patent: US6229041 B1, 2001 ;
反应条件
1: (i) LDA, (ii) /BRN= 3572572/, (iii) N2H4*H2O
2: (i) nBuNO2, aq. HCl, (ii) /BRN= 741933/, Et3N
View Scheme
参考文献
Boggs,N.T. et al.
Journal of Organic Chemistry, 1979 , vol. 44, p. 2262 - 2269
反应条件
1: 90 percent / Na / tetrahydrofuran / Ambient temperature
2: aq. KOH / methanol / 2 h / Ambient temperature
View Scheme
参考文献
Somlai, Csaba; Penke, Botond; Peter, Antal
Journal fur Praktische Chemie - Chemiker - Zeitung, 1997 , vol. 339, # 5 p. 464 - 466
反应条件
(i) Et2NH, (ii) aq. NaOH, MeOH; Multistep reaction;
参考文献
Photaki,I.
Journal of the American Chemical Society, 1963 , vol. 85, p. 1123 - 1126
