1: 80 percent / PBr3, pyridine / toluene / 1 h / -10 °C 2: 1.) DBU, 2.) 1 M aq. HCl / 1.) toluene, reflux, 5 h, 2.) THF, 25 deg C, 5 h View Scheme

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '3924730', constants.ctx, '0')">lithium</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '102391', constants.ctx, '0')">tetrahydrofuran</a> <br />&nbsp;1.) 10-15 deg C, 2.) r.t., 1 h;&nbsp;<br /> &nbsp;