4-(二苄基氨基)环己酮合成路线 （共 23 条）
反应条件
sodium tris(acetoxy)borohydride; potassium carbonate in dichloromethane
T=20°C; 12 h;
参考文献
BOEHRINGER INGELHEIM INTERNATIONAL GMBH; BOEHRINGER INGELHEIM PHARMA GMBH and CO. KG
Patent: WO2006/18182 A1, 2006 ;
Location in patent: Page/Page column 73 ;
WO 2006/018182 A1
Title/Abstract Full Text Show Details
BOEHRINGER INGELHEIM INTERNATIONAL GMBH; BOEHRINGER INGELHEIM PHARMA GMBH and CO. KG
Patent: WO2006/18185 A2, 2006 ;
Location in patent: Page/Page column 73 ;
WO 2006/018185 A2
反应条件
1.1: sodium acetate; sodium tris(acetoxy)borohydride / acetonitrile / 12 h / 20 - 30 °C / pH 6 - 7
1.2: pH 8
2.1: hydrogen; acetic acid / palladium 10 on activated carbon / methanol / 12 h / 20 - 30 °C / 2280.15 Torr
View Scheme
参考文献
SHANGHAI HENGRUI PHARMACEUTICAL CO., LTD.; JIANGSU HENGRUI MEDICINE CO., LTD.
Patent: US2012/184543 A1, 2012 ;
反应条件
sodium tris(acetoxy)borohydride in dichloromethane
T=20°C; 12 h;
参考文献
BOEHRINGER INGELHEIM INTERNATIONAL GMBH; BOEHRINGER INGELHEIM PHARMA GMBH and CO. KG
Patent: WO2006/18182 A1, 2006 ;
Location in patent: Page/Page column 72-73 ;
WO 2006/018182 A1
Title/Abstract Full Text Show Details
BOEHRINGER INGELHEIM INTERNATIONAL GMBH; BOEHRINGER INGELHEIM PHARMA GMBH and CO. KG
Patent: WO2006/18185 A2, 2006 ;
Location in patent: Page/Page column 72-73 ;
WO 2006/018185 A2
