3-溴-2-甲基-1H-吲哚合成路线 （共 4 条）
反应条件
bromine in N,N-dimethyl-formamide T=20°C; 4 h;
参考文献
Pathak, Rakhi; Nhlapo, Johanna M.; Govender, Sameshnee; Michael, Joseph P.; Van Otterlo, Willem A. L.; De Koning, Charles B.
Tetrahedron, 2006 , vol. 62, # 12 p. 2820 - 2830
反应条件
1: 82 percent / NaOH / benzene
2: 90 percent / NBS; AIBN / CCl4
3: 80 percent / K2CO3 / dimethylformamide / 12 h / 20 °C
4: 33 percent / nBu3SnH; AIBN / toluene / 48 h / Heating
View Scheme
参考文献
Kannadasan, Sathananthan; Srinivasan, Panayencheri C.
Synthetic Communications, 2004 , vol. 34, # 7 p. 1325 - 1335
反应条件
1: sodium hydride / N,N-dimethyl-formamide
2: dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II) dichloromethane adduct; potassium acetate / dimethyl sulfoxide / 12 h / 80 °C
View Scheme
参考文献
Kaila, Neelu; Follows, Bruce; Leung, Louis; Thomason, Jennifer; Huang, Adrian; Moretto, Alessandro; Janz, Kristin; Lowe, Michael; Mansour, Tarek S.; Hubeau, Cedric; Page, Karen; Morgan, Paul; Fish, Susan; Xu, Xin; Williams, Cara; Saiah, Eddine
Journal of Medicinal Chemistry, 2014 , vol. 57, # 4 p. 1299 - 1322
反应条件
sodium hydride in tetrahydrofuran
18 h;
参考文献
Pathak, Rakhi; Nhlapo, Johanna M.; Govender, Sameshnee; Michael, Joseph P.; Van Otterlo, Willem A. L.; De Koning, Charles B.
Tetrahedron, 2006 , vol. 62, # 12 p. 2820 - 2830
