5-(4-氨基苯基)-4-甲基-4H-[1,2,4]噻唑-3-硫醇合成路线 （共 10 条）
反应条件
sodium sulfide; ammonium chloride in water T=70 - 100°C;
参考文献
Kolmakov, Kirill A.
Journal of Heterocyclic Chemistry, 2008 , vol. 45, # 4 p. 1215 - 1220
反应条件
sodium hydroxide 4 h; Heating;
参考文献
Rollas; Kalyoncuoglu; Sur-Altiner; Yegenoglu
Pharmazie, 1993 , vol. 48, # 4 p. 308 - 309
反应条件
sodium hydroxide T=150°C; 0.05 h; Microwave irradiation;
参考文献
Samanta, Sanjay; Lim, Ting Liang; Lam, Yulin
ChemMedChem, 2013 , vol. 8, # 6 p. 994 - 1001
反应条件
1: ethanol / Heating 2: aq. NaOH / Heating View Scheme
参考文献
Farmaco, , vol. 59, # 11 p. 893 - 901
反应条件
1: hydrazine hydrate / ethanol / Heating 2: 1 / Heating 3: aq. NaOH / Heating View Scheme
参考文献
Farmaco, , vol. 57, # 7 p. 583 - 588
反应条件
1: diethyl ether 2: H2N-NH2*H2O / ethanol / Heating 3: ethanol / Heating 4: 2 N aq. NaOH / Heating View Scheme
参考文献
Bioorganic & Medicinal Chemistry Letters, , vol. 11, # 13 p. 1703 - 1708
反应条件
sodium hydroxide in water 4 h; Heating;
参考文献
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, , vol. 46, # 1 p. 185 - 191
反应条件
1: sulfuric acid / 0.25 h / 130 °C / |Microwave irradiation 2: hydrazine hydrate / 0.33 h / |Reflux 3: tetrahydrofuran / 0.13 h / 130 °C / |Microwave irradiation 4: sodium hydroxide / 0.05 h / 150 °C / |Microwave irradiation View Scheme
参考文献
ChemMedChem, , vol. 8, # 6 p. 994 - 1001
反应条件
1: hydrazine hydrate / 0.33 h / |Reflux 2: tetrahydrofuran / 0.13 h / 130 °C / |Microwave irradiation 3: sodium hydroxide / 0.05 h / 150 °C / |Microwave irradiation View Scheme
参考文献
ChemMedChem, , vol. 8, # 6 p. 994 - 1001
反应条件
1: tetrahydrofuran / 0.13 h / 130 °C / |Microwave irradiation 2: sodium hydroxide / 0.05 h / 150 °C / |Microwave irradiation View Scheme
参考文献
ChemMedChem, , vol. 8, # 6 p. 994 - 1001
