4-甲氧基-1,3-异苯并呋喃二酮合成路线 （共 29 条）
反应条件
1: 1) s-BuLi, N,N,N,N-tetramethylethylene diamine / 1) THF, cyclohexane, -78 deg C, 1 h, 2) to room temperature, 12 h 2: 10percent aq. HClO4 / 24 h / Heating 3: AcCl / 6 h View Scheme
参考文献
De Silva; Reed; Billedeau; Wang; Norris; Snieckus
Tetrahedron, 1992 , vol. 48, # 23 p. 4863 - 4878
反应条件
1: 10percent aq. HClO4 / 24 h / Heating 2: AcCl / 6 h View Scheme
参考文献
De Silva; Reed; Billedeau; Wang; Norris; Snieckus
Tetrahedron, 1992 , vol. 48, # 23 p. 4863 - 4878
反应条件
sodium hydroxide; potassium permanganate
参考文献
Bentley; Robinson; Weizmann
Journal of the Chemical Society, 1907 , vol. 91, p. 109
反应条件
N,N,N',N,-tetramethylethylenediamine; sec.-butyllithium 1) THF, cyclohexane, -78 deg C, 1 h, 2) to room temperature, 12 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
De Silva; Reed; Billedeau; Wang; Norris; Snieckus
Tetrahedron, 1992 , vol. 48, # 23 p. 4863 - 4878
反应条件
1: NaOH-solution 2: potassium permanganate; diluted NaOH-solution View Scheme
参考文献
Bentley; Robinson; Weizmann
Journal of the Chemical Society, 1907 , vol. 91, p. 109
反应条件
thionyl chloride T=20°C; 18 h; Title compound not separated from byproducts;
参考文献
Gupta, Dahmendra N.; Hodge, Philip; Hurley, Peter N.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1989 , p. 391 - 394
反应条件
thionyl chloride T=20°C; 18 h; Title compound not separated from byproducts;
参考文献
Gupta, Dahmendra N.; Hodge, Philip; Hurley, Peter N.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1989 , p. 391 - 394
反应条件
ethanol; trimethylsilylazide 1.) benzene, reflux, 3 h and 100 deg C, 16 h.; Yield givenMultistep reaction. Yields of byproduct given;
参考文献
Journal of Organic Chemistry, , vol. 63, # 20 p. 6797 - 6801
反应条件
n-butyllithium 1.) ether, hexane, 25 deg C, 6 d, 2.) a) -78 deg C, 1 h, b) 25 deg C, 18 h; Yield given. Multistep reaction. Further byproducts given. Yields of byproduct given;
参考文献
Hansen Jr.; Pappo; Garland
Journal of Organic Chemistry, 1988 , vol. 53, # 18 p. 4244 - 4253
反应条件
n-butyllithium 1.) ether, hexane, 25 deg C, 6 d, 2.) a) -78 deg C, 1 h, b) 25 deg C, 18 h; Multistep reaction. Further byproducts given. Yields of byproduct given;
参考文献
Hansen Jr.; Pappo; Garland
Journal of Organic Chemistry, 1988 , vol. 53, # 18 p. 4244 - 4253
