2-N-boc-1,2-丙二胺合成路线 （共 4 条）
反应条件
lithium aluminium tetrahydride in tetrahydrofuran T=-10°C;
参考文献
Gardiner, John M.; Loyns, Colin R.
Tetrahedron, 1995 , vol. 51, # 42 p. 11515 - 11530
反应条件
in ethanol 16 h; Reflux;
参考文献
GLAXOSMITHKLINE LLC; BANKA, Anna; CATALANO, John, G.; CHONG, Pek, Yoke; FANG, Jing; GARRIDO, Dulce, Maria; PEAT, Andrew, James; PRICE, Daniel, J.; SHOTWELL, John, Brad; TAI, Vincent; ZHANG, Huichang
Patent: WO2011/41713 A2, 2011 ;
Location in patent: Page/Page column 229 ;
反应条件
1: 100 percent / Et3N / CH2Cl2 / 0 deg C, 3 h; r.t., 1 h 2: 41 percent / NaN3, titanium(IV) isopropoxide / dimethylformamide / 24 h / 60 °C 3: 85 percent / LiAlH4 / tetrahydrofuran / -10 °C View Scheme
参考文献
Gardiner, John M.; Loyns, Colin R.
Tetrahedron, 1995 , vol. 51, # 42 p. 11515 - 11530
反应条件
1: 41 percent / NaN3, titanium(IV) isopropoxide / dimethylformamide / 24 h / 60 °C 2: 85 percent / LiAlH4 / tetrahydrofuran / -10 °C View Scheme
参考文献
Gardiner, John M.; Loyns, Colin R.
Tetrahedron, 1995 , vol. 51, # 42 p. 11515 - 11530
