5-氰基-1H-吲哚-3-丙酸合成路线 (共 3 条)
反应条件
acetic anhydride; acetic acid 15 h; Heating;
参考文献
Agarwal; Jalluri; DeWitt Blanton Jr.; Taylor
Synthetic Communications, 1993 , vol. 23, # 8 p. 1101 - 1110
反应条件
1: 72.6 percent / N-methyl-2-pyrrolidone / 4.5 h / Heating 2: 45 percent / AcOH, Ac2O / 15 h / Heating View Scheme
参考文献
Agarwal; Jalluri; DeWitt Blanton Jr.; Taylor
Synthetic Communications, 1993 , vol. 23, # 8 p. 1101 - 1110
反应条件
1: 40.5 percent / diphenylphosphonic azide (DPPA), Et3N / 2-methyl-propan-2-ol / 9 h / Heating
2: 7 percent / 30percent aq. H2O2 / methanol; tetrahydrofuran / 0.25 h / 15 °C
View Scheme
参考文献
Agarwal; Jalluri; DeWitt Blanton Jr.; Taylor
Synthetic Communications, 1993 , vol. 23, # 8 p. 1101 - 1110