2-甲基-4-三氟甲基嘧啶-5-羧酸合成路线 （共 3 条）
反应条件
sodium hydroxide in tetrahydrofuran Hydrolysis;
参考文献
Palanki; Erdman; Gayo-Fung; Shevlin; Sullivan; Goldman; Ransone; Bennett; Manning; Suto
Journal of medicinal chemistry, 2000 , vol. 43, # 21 p. 3995 - 4004
反应条件
1: 58 percent / NaOEt / ethanol / 6 h / Heating 2: 82 percent / aq. NaOH / tetrahydrofuran View Scheme
参考文献
Journal of medicinal chemistry, , vol. 43, # 21 p. 3995 - 4004
反应条件
1: 72 percent / EtONa / ethanol / 24 h / Heating 2: 65 percent / 2 N NaOH / Ambient temperature View Scheme
参考文献
Farmaco, , vol. 48, # 3 p. 335 - 355
