4-(4-氟苯基)-2,6-二苯基吡啶合成路线 （共 12 条）
反应条件
sodium hydrogensulfite; copper(I) bromide in dimethyl sulfoxide
T=120°C; 2.5 h; Inert atmosphere;
参考文献
Ren, Zhi-Hui; Zhang, Zhi-Yuan; Yang, Bing-Qin; Wang, Yao-Yu; Guan, Zheng-Hui
Organic Letters, 2011 , vol. 13, # 19 p. 5394 - 5397
反应条件
ammonium hydrogen carbonate; DPAT
T=120°C; 7 h; Neat (no solvent); regioselective reaction;
参考文献
Li, Jianjun; He, Ping; Yu, Chuanming
Tetrahedron, 2012 , vol. 68, # 22 p. 4138 - 4144
反应条件
urea; Bi(NO3)3/ZnCl2 on Al2O3 in chloroform
T=130°C; 0.383333 h; microwave irradiation;
参考文献
Verma, Anil K.; Koul, Summon; Pannu, Ajay P.S.; Razdan, Tej K.
Tetrahedron, 2007 , vol. 63, # 36 p. 8715 - 8722
反应条件
urea; aluminum oxide; Bi(NO3)3
T=130°C;
参考文献
Kumar, Anil; Koul, Summon; Razdan, Tej K.; Kapoor, Kamal K.
Tetrahedron Letters, 2006 , vol. 47, # 5 p. 837 - 842
反应条件
1: With tetrakis(triphenylphosphine) palladium(0); sodium acetate in N,N-dimethyl-formamide
T=80°C; 12 h; Inert atmosphere;
2: in N,N-dimethyl-formamide
T=80°C; 12 h;
参考文献
He, Zhi; Dobrovolsky, Dennis; Trinchera, Piera; Yudin, Andrei K.
Organic Letters, 2013 , vol. 15, # 2 p. 334 - 337
反应条件
oxygen; copper(II) bis(trifluoromethanesulfonate)
T=100°C; 20 h; Sealed tube;
参考文献
Huang, Huawen; Ji, Xiaochen; Wu, Wanqing; Huang, Liangbin; Jiang, Huanfeng
Journal of Organic Chemistry, 2013 , vol. 78, # 8 p. 3774 - 3782
反应条件
1: 3 h / 100 °C
2: sodium hydrogensulfite; copper(I) bromide / dimethyl sulfoxide / 2.5 h / 120 °C / Inert atmosphere
View Scheme
参考文献
Ren, Zhi-Hui; Zhang, Zhi-Yuan; Yang, Bing-Qin; Wang, Yao-Yu; Guan, Zheng-Hui
Organic Letters, 2011 , vol. 13, # 19 p. 5394 - 5397
反应条件
1.1: magnesium sulfate / dichloromethane / 20 °C
2.1: tetrakis(triphenylphosphine) palladium(0); sodium acetate / N,N-dimethyl-formamide / 12 h / 80 °C / |Inert atmosphere
2.2: air / 12 h / 80 °C
View Scheme
参考文献
He, Zhi; Dobrovolsky, Dennis; Trinchera, Piera; Yudin, Andrei K.
Organic Letters, 2013 , vol. 15, # 2 p. 334 - 337
反应条件
1.1: magnesium sulfate / dichloromethane / 20 °C
2.1: tetrakis(triphenylphosphine) palladium(0); sodium acetate / N,N-dimethyl-formamide / 12 h / 80 °C / |Inert atmosphere
2.2: air / 12 h / 80 °C
View Scheme
参考文献
He, Zhi; Dobrovolsky, Dennis; Trinchera, Piera; Yudin, Andrei K.
Organic Letters, 2013 , vol. 15, # 2 p. 334 - 337
反应条件
aluminum oxide; Bi(NO3)3
T=130°C;
参考文献
Kumar, Anil; Koul, Summon; Razdan, Tej K.; Kapoor, Kamal K.
Tetrahedron Letters, 2006 , vol. 47, # 5 p. 837 - 842
