sodium hydride in N,N-dimethyl-formamide; mineral oil T=120°C; 1 h;

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '1879369', constants.ctx, '0')">[bis(acetoxy)iodo]benzene</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '605264', constants.ctx, '0')">1,2-dichloro-ethane</a> <br />T=20&deg;C;&nbsp;1&nbsp;h;&nbsp;<br /> &nbsp;

<b>Multi-step reaction with 6 steps<br /> </b>1: palladium diacetate; copper diacetate; potassium carbonate / N,N-dimethyl-formamide / 15 h / 80 &deg;C / |Inert atmosphere<br />2: sodium hydroxide / tetrahydrofuran / 2 h / 20 &deg;C<br />3: sodium hydroxide / water; ethanol / 15 h / 80 &deg;C<br />4: thionyl chloride / dichloromethane / 1 h / 20 &deg;C<br />5: dichloromethane / 2 h / -20 - 20 &deg;C<br />6: [bis(acetoxy)iodo]benzene / 1,2-dichloro-ethane / 1 h / 20 &deg;C<br /> <br /> &nbsp;