1: [bis(acetoxy)iodo]benzene / 1,2-dichloro-ethane / 1 h / 20 °C 2: sodium hydride / N,N-dimethyl-formamide; mineral oil / 1 h / 120 °C View Scheme

<b>Multi-step reaction with 5 steps<br /> </b>1: palladium diacetate; copper diacetate; potassium carbonate / N,N-dimethyl-formamide / 15 h / 80 &deg;C / |Inert atmosphere<br />2: sodium hydroxide / tetrahydrofuran / 2 h / 20 &deg;C<br />3: sodium hydroxide / water; ethanol / 15 h / 80 &deg;C<br />4: thionyl chloride / dichloromethane / 1 h / 20 &deg;C<br />5: dichloromethane / 2 h / -20 - 20 &deg;C<br /> <br /> &nbsp;