Davies, Stephen G.; Garrido, Narciso M.; Ichihara, Osamu; Walters, Iain A. S.
Journal of the Chemical Society, Chemical Communications, 1993 , # 14 p. 1153 - 1155
1: (S)-N-benzyl-α-methylbenzylamine With n-butyllithium in tetrahydrofuran; hexane T=-78°C; 0.5 h; Inert atmosphere; 2: tert-butyl cinnamoate in tetrahydrofuran; hexane T=-78°C; 2 h; Inert atmosphere; 3: With water; ammonium chloride in tetrahydrofuran; hexane T=-78 - 20°C; Inert atmosphere; optical yield given as percent dediastereoselective reaction;
参考文献
Davies, Stephen G.; Foster, Emma M.; McIntosh, Catherine R.; Roberts, Paul M.; Rosser, Timothy E.; Smith, Andrew D.; Thomson, James E.
Tetrahedron Asymmetry, 2011 , vol. 22, # 10 p. 1035 - 1050
in tetrahydrofuran T=-78°C; 2 h; Inert atmosphere; diastereoselective reaction;
参考文献
Davies, Stephen G.; Fletcher, Ai M.; Lee, James A.; Roberts, Paul M.; Souleymanou, Myriam Y.; Thomson, James E.; Zammit, Charlotte M.
Organic and Biomolecular Chemistry, 2014 , vol. 12, # 17 p. 2702 - 2728
1.1: n-BuLi / tetrahydrofuran; hexane / 0.5 h / -78 °C 1.2: 96 percent / tetrahydrofuran; hexane / 3 h / -78 °C 2.1: 89 percent / H2; acetic acid / Pd(OH)2/C / methanol; H2O / 24 h / 20 °C / 760.05 Torr 3.1: 96 percent / trifluoroacetic acid / CH2Cl2 / 15 h / 20 °C View Scheme
参考文献
Bull, Steven D.; Davies, Stephen G.; Kelly, Peter M.; Gianotti, Massimo; Smith, Andrew D.
Journal of the Chemical Society. Perkin Transactions 1, 2001 , # 23 p. 3106 - 3111
1.1: n-BuLi / tetrahydrofuran; hexane / 0.5 h / -78 °C 1.2: 96 percent / tetrahydrofuran; hexane / 3 h / -78 °C 2.1: 89 percent / H2; acetic acid / Pd(OH)2/C / methanol; H2O / 24 h / 20 °C / 760.05 Torr 3.1: 96 percent / trifluoroacetic acid / CH2Cl2 / 15 h / 20 °C View Scheme
参考文献
Bull, Steven D.; Davies, Stephen G.; Kelly, Peter M.; Gianotti, Massimo; Smith, Andrew D.
Journal of the Chemical Society. Perkin Transactions 1, 2001 , # 23 p. 3106 - 3111
1.1: n-BuLi / tetrahydrofuran; hexane / 0.5 h / -78 °C 1.2: 96 percent / tetrahydrofuran; hexane / 3 h / -78 °C 2.1: 89 percent / H2; acetic acid / Pd(OH)2/C / methanol; H2O / 24 h / 20 °C / 760.05 Torr 3.1: 96 percent / trifluoroacetic acid / CH2Cl2 / 15 h / 20 °C View Scheme
参考文献
Bull, Steven D.; Davies, Stephen G.; Kelly, Peter M.; Gianotti, Massimo; Smith, Andrew D.
Journal of the Chemical Society. Perkin Transactions 1, 2001 , # 23 p. 3106 - 3111
