2-氯-5-氟-1,3-二甲苯合成路线 （共 9 条）
反应条件
C94H134O4P2Pd2; cesium fluoride in toluene T=110°C; 14 h; Inert atmosphere;
参考文献
Lee, Hong Geun; Milner, Phillip J.; Buchwald, Stephen L.
Organic Letters, 2013 , vol. 15, # 21 p. 5602 - 5605
反应条件
chlorine; iron(III) chloride
反应条件
1: (i) PCl5, (ii) aq. NH3 2: aq. NaOH, Br2 3: (i) aq. HCl, NaNO2, (ii) HPF6 4: H2 / Pd-C 5: (i) aq. HCl, NaNO2, (ii) CuCl, aq. HCl View Scheme
参考文献
Journal of the American Chemical Society, , vol. 89, # 2 p. 390 - 394
反应条件
1: H2 / Pd-C 2: (i) aq. HCl, NaNO2, (ii) CuCl, aq. HCl View Scheme
参考文献
Journal of the American Chemical Society, , vol. 89, # 2 p. 390 - 394
反应条件
1: (i) aq. HCl, NaNO2, (ii) HPF6 2: H2 / Pd-C 3: (i) aq. HCl, NaNO2, (ii) CuCl, aq. HCl View Scheme
参考文献
Journal of the American Chemical Society, , vol. 89, # 2 p. 390 - 394
反应条件
1: aq. NaOH, Br2 2: (i) aq. HCl, NaNO2, (ii) HPF6 3: H2 / Pd-C 4: (i) aq. HCl, NaNO2, (ii) CuCl, aq. HCl View Scheme
参考文献
Journal of the American Chemical Society, , vol. 89, # 2 p. 390 - 394
反应条件
1: |Inert atmosphere 2: cesium fluoride; C94H134O4P2Pd2 / toluene / 14 h / 110 °C / |Inert atmosphere View Scheme
参考文献
Organic Letters, , vol. 15, # 21 p. 5602 - 5605
反应条件
(i) aq. HCl, NaNO2, (ii) CuCl, aq. HCl; Multistep reaction;
参考文献
Journal of the American Chemical Society, , vol. 89, # 2 p. 390 - 394
