4-羟基-1-苯基-1,2-二氢喹啉-2-酮合成路线 （共 20 条）
反应条件
1: 78 percent / tetrahydrofuran; diethyl ether / 1) 0 deg C, 1 h, 2) 20 deg C, 16 h 2: 61 percent / 1,3,5-trimethyl-benzene / 16 h / 165 °C 3: 42 percent / KOH / H2O / 4 h / Heating View Scheme
参考文献
Chemische Berichte, , vol. 126, # 3 p. 841 - 844
反应条件
1: 61 percent / 1,3,5-trimethyl-benzene / 16 h / 165 °C 2: 42 percent / KOH / H2O / 4 h / Heating View Scheme
参考文献
Chemische Berichte, , vol. 126, # 3 p. 841 - 844
参考文献
Pandey, G.; Muralikrishna, C.; Bhalerao, U. T.
Tetrahedron, 1989 , vol. 45, p. 6867 - 6874
反应条件
phosphorous pentoxide; sulfuric acid; acetic acid T=20°C; 0.75 h;
参考文献
Helvetica Chimica Acta, , vol. 95, # 8 p. 1352 - 1372
反应条件
trichlorophosphate in 1,4-dioxane T=120°C; 0.416667 h; microwave irradiation;
参考文献
Hashim, Jamshed; Glasnov, Toma N.; Kremsner, Jennifer M.; Kappe, C. Oliver
Journal of Organic Chemistry, 2006 , vol. 71, # 4 p. 1707 - 1710
反应条件
1: 94 percent / conc. HNO3, NaNO2 / acetic acid / 0.5 h 2: 96 percent / triethylamine, phosphoryl chloride / 1 h / Heating 3: 96 percent / pyridine / various solvent(s) / 0.5 h / Ambient temperature View Scheme
参考文献
Journal of Heterocyclic Chemistry, , vol. 29, # 1 p. 225 - 231
反应条件
Food Red No. 105 in methanol 42 h; Photolysis;
参考文献
Ye, Jia-Hai; Qin, Zhichun; Zhou, Bin; Zhang, Wenchao; Tian, Guirong; Yuan, Lei; Xu, Jian-Hua
Organic Preparations and Procedures International, 2009 , vol. 41, # 1 p. 83 - 87
反应条件
1: 1-phenyl-4-hydroxy-2(1H)-quinolinone With sodium hydroxide in water
T=4 - 80°C;
2: chloroform in water
T=80°C; Reimer-Tiemann reaction; 13.6667 h;
3: With sulfuric acid in water
T=20°C;
参考文献
Bhudevi; Ramana; Mudiraj, Anwita; Reddy
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2009 , vol. 48, # 2 p. 255 - 260
反应条件
1: 66 percent / ethane-1,2-diol / 190 °C
2: 81 percent / 2 N aq. NaOH / dioxane / 2 h / 100 °C
View Scheme
参考文献
Fiala, Werner; Stadlbauer, Wolfgang
Journal fuer Praktische Chemie/Chemiker-Zeitung, 1993 , vol. 335, # 2 p. 128 - 134
反应条件
triethylamine in toluene
5 h; Heating;
参考文献
Stadlbauer, Wolfgang; Hojas, Gerhard
Journal of Heterocyclic Chemistry, 2004 , vol. 41, # 5 p. 681 - 690
