反应条件
1: thionyl chloride / -10 - 20 °C
2: potassium carbonate; tBuNH2·BH3 / 1,4-dioxane; water / 48 h / |Reflux
3: sodium hydroxide; water / methanol / |Reflux
4: oxalyl dichloride / dichloromethane; N,N-dimethyl-formamide / 2 h / 0 - 20 °C
View Scheme
参考文献
Liu, Xia; Chan, Chi-Bun; Qi, Qi; Ye, Keqiang; Xiao, Ge; Luo, Hongbo R.; He, Xiaolin
Journal of Medicinal Chemistry, 2012 , vol. 55, # 19 p. 8524 - 8537,14