2-羟基-4-氧代-1H-喹啉-3-甲腈合成路线 （共 15 条）
反应条件
1: TEA / 1 h / 20 °C 2: 1,2-dichloro-benzene / 180 °C View Scheme
参考文献
Mekheimer, Ramadan Ahmed; Elgemeie, Galal Hamza; Kappe, Thomas
Journal of Chemical Research, 2005 , # 2 p. 82 - 85
反应条件
triethylamine solid-phase synthesis; 1.) DMF, RT; 2.) toluene, 80 deg C, 24 h; Yield given. Multistep reaction;
参考文献
Sim, Mui Mui; Lee, Cheng Leng; Ganesan
Tetrahedron Letters, 1998 , vol. 39, # 35 p. 6399 - 6402
反应条件
in sulfuric acid; nitric acid
参考文献
BASF Aktiengesellschaft
Patent: US4927935 A1, 1990 ;
反应条件
trichlorophosphate
T=60°C; 1 h;
参考文献
BAYER PHARMACEUTICALS CORPORATION
Patent: WO2006/34491 A2, 2006 ;
Location in patent: Page/Page column 134 ;
WO 2006/034491 A2
参考文献
Gabriel
Chemische Berichte, 1918 , vol. 51, p. 1509
