N-[芴甲氧羰基]-D-天冬氨酸 4-苄酯合成路线 (共 6 条)
反应条件
1: toluene-4-sulfonic acid; (+/-)-Aspartic acid; benzyl alcohol in benzene Heating; 2: (9H-Fluoren-9-yl)-methyl chloroformate With sodium hydroxide; ethanol; copper(II) sulfate in 1,4-dioxane; water pH=8; Further stages.;
参考文献
Boyer; Stanchev; Fairbanks; Davis
Chemical communications (Cambridge, England), 2001 , # 19 p. 1908 - 1909
参考文献
Kisfaludy, Lajos; Schoen, Istvan
Synthesis, 1983 , # 4 p. 325 - 327
反应条件
1: POCl3; pyridine 2: H2 / Pd/C View Scheme
参考文献
Van Ameijde, Jeroen; Albada, H. Bauke; Liskamp, Rob M.J.
Journal of the Chemical Society. Perkin Transactions 1, 2002 , # 8 p. 1042 - 1049
反应条件
1: POCl3; pyridine 2: H2 / Pd/C View Scheme
参考文献
Van Ameijde, Jeroen; Albada, H. Bauke; Liskamp, Rob M.J.
Journal of the Chemical Society. Perkin Transactions 1, 2002 , # 8 p. 1042 - 1049
反应条件
thionyl chloride; N,N-dimethyl-formamide in dichloromethane 1 h; Ambient temperature;
参考文献
Carpino, Louis A.; Cohen, Beri J.; Stephens, Kenton E.; Sadat-Aalaee, S. Yahya; Tien, Jien-Heh; Langridge, Denton C.
Journal of Organic Chemistry, 1986 , vol. 51, # 19 p. 3732 - 3734
反应条件
dicyclohexyl-carbodiimide in ethyl acetate
0 deg C, 1 h; r.t., 1 h;
参考文献
Kisfaludy, Lajos; Schoen, Istvan
Synthesis, 1983 , # 4 p. 325 - 327