2,3-二甲基苯甲酸甲酯合成路线 （共 16 条）
反应条件
thionyl chloride Heating / reflux;
参考文献
PFIZER PRODUCTS INC.
Patent: WO2008/53319 A1, 2008 ;
Location in patent: Page/Page column 55 ;
反应条件
caesium carbonate in N,N-dimethyl-formamide T=20°C; 2 h;
参考文献
US2009/275583 A1, ;
Page/Page column 31 ;
反应条件
thionyl chloride in N,N-dimethyl-formamide
反应条件
1.1: Zn; TiCl4 / tetrahydrofuran / 14 h / 4 °C 1.2: 85 percent / tetrahydrofuran / 0.5 h / 20 °C 2.1: 30 percent Chromat. / silica / 0.67 h / 700 °C / 0.01 Torr View Scheme
参考文献
Australian Journal of Chemistry, , vol. 53, # 5 p. 435 - 437
反应条件
in methanol T=65°C; 2 h; Yield given. Yields of byproduct given;
参考文献
Helvetica Chimica Acta, , vol. 81, # 2 p. 251 - 267
反应条件
1: 40 percent / HBr / diazotization 2: 1.) Mg / 1.) ether, 2.) ether, reflux, 2 h; room temp., overnight View Scheme
参考文献
Monatshefte fur Chemie, , vol. 127, # 2 p. 185 - 200
反应条件
triphenylmethane tetrafluoroborate
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 2339 - 2342
反应条件
magnesium 1.) ether, 2.) ether, reflux, 2 h; room temp., overnight; Yield given. Multistep reaction;
参考文献
Monatshefte fur Chemie, , vol. 127, # 2 p. 185 - 200
反应条件
magnesium 1.) ether, 2.) ether, reflux, 2 h; room temp., overnight; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Monatshefte fur Chemie, , vol. 127, # 2 p. 185 - 200
参考文献
Magnetic Resonance in Chemistry, , vol. 42, # 10 p. 844 - 851
