1: 90 percent / iBu2AlH / hexane; toluene / 4 h / -78 °C 2: 12 percent / NaH / dimethylformamide / 1.5 h / Ambient temperature View Scheme

1: 90 percent / iBu2AlH / hexane; toluene / 4 h / -78 °C 2: 12 percent / NaH / dimethylformamide / 1.5 h / Ambient temperature 3: pyridinium p-toluenesulfonate / methanol / 30 h / Heating View Scheme

<b>Multi-step reaction with 2 steps<br /> </b>1: 61 percent / pyridine / 10 h / Ambient temperature<br />2: 98 percent / imidazole / dimethylformamide / 10 h / Ambient temperature<br /> <br /> &nbsp;

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '103853', constants.ctx, '0')">1H-imidazole</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '605365', constants.ctx, '0')">N,N-dimethyl-formamide</a> <br />10&nbsp;h;&nbsp;&nbsp;Ambient temperature;&nbsp;<br /> &nbsp;

<b>Multi-step reaction with 2 steps<br /> </b>1: 61 percent / pyridine / 10 h / Ambient temperature<br />2: 98 percent / imidazole / dimethylformamide / 10 h / Ambient temperature<br /> <br /> &nbsp;