甲基 3-苯基-DL-丙氨酸酯合成路线 （共 43 条）
反应条件
1: 1.) PyBOP, (i-Pr)2NEt / 1.) THF, r.t., 40 min, 2.) THF, r.t.
2: p-TsOH / tetrahydrofuran / 12 h / Heating
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参考文献
Aguilar, Nuria; Moyano, Albert; Pericas, Miquel A.; Riera, Antoni
Synthesis, 1998 , # 3 p. 313 - 316
反应条件
1: diisobutylaluminium hydride / toluene / 2 h / -78 °C / |Inert atmosphere
2: ethyl acetate; water / 1 h / 20 °C
View Scheme
参考文献
Rojas, Nora; Grillasca, Yvonne; Acosta, Alejandrina; Audelo, Irene; De La Mora, Gustavo Garcia
Journal of Heterocyclic Chemistry, 2013 , vol. 50, # 4 p. 982 - 984
反应条件
1: sodium borohydride / methanol / 20 °C
2: 3 g / sodium azide; trifluoromethanesulfonic anhydride; pyridine / copper(II) sulfate / CH2Cl2 / 18 h
3: 36 percent / pyridinium chlorochromate / CH2Cl2 / 0 - 20 °C
View Scheme
参考文献
Fan, Qiu-Hua; Ni, Nan-Ting; Li, Qin; Zhang, Li-He; Ye, Xin-Shan
Organic Letters, 2006 , vol. 8, # 5 p. 1007 - 1009
