2-(4-吡啶基)-2-丙醇合成路线 (共 13 条)
反应条件
methyllithium in tetrahydrofuran; diethyl ether
参考文献
British Technology Group Limited
Patent: US5595995 A1, 1997 ;
反应条件
in diethyl ether; benzene T=25°C; 1.5 h; ketone/MeLi ratio 1:2;
参考文献
Epsztajn, Jan; Bieniek, Adam
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1985 , p. 213 - 220
反应条件
1: ethylmagnesium bromide; methyllithium in tetrahydrofuran; diethyl ether T=-78°C; 1 h; 2: 1-(pyridin-4-yl)ethanone in tetrahydrofuran; diethyl ether T=-78°C; 1 h;
参考文献
Organic Letters, , vol. 7, # 4 p. 573 - 576
反应条件
in diethyl ether T=0 - 20°C; 1 h;
参考文献
Journal of Organic Chemistry, , vol. 63, # 25 p. 9243 - 9251
参考文献
Journal of the Chemical Society, , p. 41,43
Chemische Berichte, , vol. 72, p. 1188,1193
参考文献
Recueil des Travaux Chimiques des Pays-Bas, , vol. 74, p. 1003,1015
反应条件
biphenyl in water; isopropyl alcohol 24 h; Irradiation; Product distribution;
参考文献
Journal of Heterocyclic Chemistry, , vol. 21, p. 1277 - 1280
参考文献
Bulletin de la Societe Chimique de France, , p. 419,420
反应条件
in N,N,N',N',N'',N''-hexamethylphosphoric triamide T=26°C; 48 h; Irradiationin the presence of m-dinitrobenzene; in the presence of di-t-butylnitroxide; different time; different temperature; Product distribution;
参考文献
Journal of Heterocyclic Chemistry, , vol. 18, p. 783 - 787
反应条件
in water; isopropyl alcohol 24 h; Irradiationconc. H2SO4 added; Product distributionMechanism;
参考文献
Journal of Heterocyclic Chemistry, , vol. 21, p. 1277 - 1280