1: With lithium carbonate in water; tert-butyl alcohol T=23°C; 0.166667 h; Resolution of racemate; 2: With 2-hydroxymethyl-pyridine; Alcalase; water; Zn(CH3COO)2*2H2O in tert-butyl alcohol T=23°C; 4 h; Resolution of racemateEnzymatic reaction; optical yield given as percent ee;
参考文献
Felten, Albert E.; Zhu, Gangguo; Aron, Zachary D.
Organic Letters, 2010 , vol. 12, # 9 p. 1916 - 1919
