3-苯基-2-丙炔-1-醇合成路线 （共 165 条）
反应条件
triethylamine in tetrahydrofuran T=-78 - 20°C;
参考文献
Guo, Hao; Qian, Rong; Guo, Yinlong; Ma, Shengming
Journal of Organic Chemistry, 2008 , vol. 73, # 20 p. 7934 - 7938
反应条件
1: tetrahydrofuran; cyclohexane / 19 h / 80 °C View Scheme
参考文献
Forgione, Pat; Wilson, Peter D.; Fallis, Alex G.
Tetrahedron Letters, 2000 , vol. 41, # 1 p. 17 - 20
反应条件
1: With pyridine; palladium diacetate; tetrabutyl-ammonium chloride in N,N-dimethyl-formamide T=100°C; P=760 Torr; 12 h; 2: With sodium hydroxide in ethanol T=20°C; 0.5 h;
参考文献
Kadnikov, Dmitry V.; Larock, Richard C.
Journal of Organic Chemistry, 2004 , vol. 69, # 20 p. 6772 - 6780
反应条件
1: crotyl alcohol With sodium hydride in tetrahydrofuran T=20°C; 2: 3-phenyl-2-propyn-1-ol (phenyl propargyl alcohol) in tetrahydrofuran T=20°C; 1 h; Further stages. Title compound not separated from byproducts.;
参考文献
Morimoto, Tsumoru; Fuji, Koji; Tsutsumi, Ken; Kakiuchi, Kiyomi
Journal of the American Chemical Society, 2002 , vol. 124, # 15 p. 3806 - 3807
反应条件
sodium hydride in N,N-dimethyl-formamide T=-20 - 20°C;
参考文献
Stuedemann, Thomas; Ibrahim-Ouali, Malika; Knochel, Paul
Tetrahedron, 1998 , vol. 54, # 7 p. 1299 - 1316
反应条件
1: 3-phenyl-2-propyn-1-ol (phenyl propargyl alcohol) With sodium hydride in tetrahydrofuran T=0 - 20°C; 2: benzyl chloride With potassium iodide in tetrahydrofuran T=20°C; 4.5 h;
参考文献
Kadnikov, Dmitry V.; Larock, Richard C.
Journal of Organic Chemistry, 2003 , vol. 68, # 24 p. 9423 - 9432
反应条件
trifluorormethanesulfonic acid T=-5 - 30°C; 4 h; Inert atmosphereIonic liquid;
参考文献
Aridoss, Gopalakrishnan; Sarca, Viorel D.; Ponder Jr, James F.; Crowe, Jessica; Laali, Kenneth K.
Organic and Biomolecular Chemistry, 2011 , vol. 9, # 7 p. 2518 - 2529
反应条件
trifluorormethanesulfonic acid T=-5 - 20°C; 6 h; Inert atmosphereIonic liquid; regioselective reaction;
参考文献
Aridoss, Gopalakrishnan; Sarca, Viorel D.; Ponder Jr, James F.; Crowe, Jessica; Laali, Kenneth K.
Organic and Biomolecular Chemistry, 2011 , vol. 9, # 7 p. 2518 - 2529
反应条件
1: pyridinium chlorochromate / CH2Cl2 / 1.5 h / Ambient temperature 2: 1.) n-butyllithium / 1.) THF, hexane, -78 deg C, 15 min, 2.) THF, hexane, RT 3: manganese dioxide / benzene / 3 h / Ambient temperature View Scheme
参考文献
Wadsworth, Donald H.; Geer, Susan M.; Detty, Michael R.
Journal of Organic Chemistry, 1987 , vol. 52, # 16 p. 3662 - 3668
反应条件
silica gel; Bobbitt's oxidant in dichloromethane
参考文献
Bobbitt, James M.
Journal of Organic Chemistry, 1998 , vol. 63, # 25 p. 9367 - 9374
