3-苯基-2-丙炔-1-醇合成路线 （共 165 条）
反应条件
4-(N,N-dimethlyamino)pyridine; triethylamine in dichloromethane
T=20°C; 16.5 h;
参考文献
Nishimoto, Yoshihiro; Okita, Aya; Yasuda, Makoto; Baba, Akio
Organic Letters, 2012 , vol. 14, # 7 p. 1846 - 1849
反应条件
1.1: manganese(IV) oxide / dichloromethane / 20 °C
2.1: n-butyllithium / tetrahydrofuran; hexane / 0.25 h / 0 °C / |Inert atmosphere
2.2: |Inert atmosphere
3.1: manganese(IV) oxide / dichloromethane / 20 °C
View Scheme
参考文献
Qiu, Yi-Feng; Yang, Fang; Qiu, Zi-Hang; Zhong, Mei-Jin; Wang, Li-Jing; Ye, Yu-Ying; Song, Bo; Liang, Yong-Min
Journal of Organic Chemistry, 2013 , vol. 78, # 23 p. 12018 - 12028
反应条件
1: NaOPh
2: CrO3*2Py
View Scheme
参考文献
Gelin,R.; Makula,D.
Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1964 , vol. 258, p. 5234 - 5236
反应条件
pyridine; phosphorus tribromide
参考文献
Andre, Virginie; Robin, Sylvie; Rousseau, Gerard
Tetrahedron Letters, 2008 , vol. 49, # 34 p. 5059 - 5062
反应条件
pyridine in diethyl ether
参考文献
Bayer Corporation
Patent: US5789434 A1, 1998 ;
US 5789434 A
参考文献
Cao; Chan; Chow
Tetrahedron Letters, 1996 , vol. 37, # 7 p. 1049 - 1052
反应条件
1: 1.) phthalimide, triphenylphosphine, diisopropyl azodicarboxylate, 2.) hydrazine hydrate / 1.) THF, RT, 3 d, 2.) THF, reflux
2: 85 percent / H2, Rh(OAc)2, Ph3P / ethyl acetate / 20 h / 70 °C / 20685.9 Torr / other (arylpropargyl)amines
View Scheme
参考文献
Campi, Eva M.; Fallon, Gary D.; Jackson, W. Roy; Nilsson, Ylva
Australian Journal of Chemistry, 1992 , vol. 45, # 7 p. 1167 - 1178
反应条件
1: aqueous acetic acid
View Scheme
参考文献
Wenus-Danilowa; Danilow
Zhurnal Obshchei Khimii, 1932 , vol. 2, p. 645,652, 653
Chem. Zentralbl., C 1933 II 47
反应条件
1: Ph3P; CBr4 / benzene / 2 h / 0 °C
2: 95 percent / Na2S / methanol / 2 h / 20 °C
3: 89 percent / Oxone / CH2Cl2 / 50 °C
4: 30 percent / KOH-Al2O3; CBr2F2 / CH2Cl2
View Scheme
参考文献
Cao; Chan; Chow
Tetrahedron Letters, 1996 , vol. 37, # 7 p. 1049 - 1052
反应条件
1: 79 percent / tri-n-butylamine, thionyl chloride / CCl4 / 1 h / Ambient temperature
View Scheme
参考文献
Chen, Tsu-yu Raymond; Anderson, Mark R.; Grossman, Steven; Peters, Dennis G.
Journal of Organic Chemistry, 1987 , vol. 52, # 7 p. 1231 - 1236
