3-(4-甲基苯基)-2-丙烯醛合成路线 （共 31 条）
反应条件
1: 88 percent / potassium hydroxide / ethanol / 0.25 h / Heating 2: 17 percent / 0.83 h / 650 °C / 0 - 0.01 Torr / further cinnamaldehyde O-alkyl oxime derivatives View Scheme
参考文献
Hickson, Clare L.; McNab, Hamish
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1984 , # 7 p. 1569 - 1572
反应条件
1: NaBH4 2: SOCl2 View Scheme
参考文献
Cignarella,G. et al.
Journal of Medicinal Chemistry, 1965 , vol. 8, p. 326 - 331
反应条件
in benzene at 35-50 °C,for 2-24 h; chromatography on Al2O3 with CH2Cl2/C6H14;
参考文献
Gmelin Handbook: Fe: Org.Verb.B5, 1.3.4.3, page 120 - 151
反应条件
1: With TsNHOH; potassium carbonate in methanol; water T=20°C; 10 h; 2: With potassium carbonate in methanol; water T=60°C; 4 h; regioselective reaction;
参考文献
Organic Letters, , vol. 11, # 17 p. 3982 - 3985
参考文献
Godfroid,J.J. et al.
Bulletin de la Societe Chimique de France, 1966 , p. 3238 - 3243
反应条件
pyridine; hydrogenchloride; 4-(N,N-dimethlyamino)pyridine
1) CH2Cl2, 0 deg C, 2) 1 h, room temp.; Yield given. Multistep reaction;
参考文献
Keinan, Ehud; Peretz, Moshe
Journal of Organic Chemistry, 1983 , vol. 48, # 26 p. 5302 - 5309
反应条件
1: 1) conc. HCl, 2) pyridine, 4-(dimethylamino)pyridine / 1) CH2Cl2, 0 deg C, 2) 1 h, room temp.
2: 18 percent / 1.5 h / Ambient temperature
View Scheme
参考文献
Keinan, Ehud; Peretz, Moshe
Journal of Organic Chemistry, 1983 , vol. 48, # 26 p. 5302 - 5309
反应条件
cesium fluoride in toluene; acetonitrile
T=75°C; 48.5 h;
参考文献
Zhang, Tiexin; Huang, Xian; Wu, Luling
European Journal of Organic Chemistry, 2012 , # 18 p. 3507 - 3519
反应条件
(R)-diphenylprolinol trimethylsilyl ether; anhydrous lithium acetate in methanol
T=20°C; Michael condensation; 48 h; optical yield given as percent eeenantioselective reaction;
参考文献
Li, Wenjun; Wu, Wenbin; Yang, Juanjuan; Liang, Xinmiao; Ye, Jinxing
Synthesis, 2011 , # 7 p. 1085 - 1091
反应条件
palladium 10 on activated carbon; hydrogen in methanol
1.5 h;
参考文献
Baechle, Florian; Duschmale, Joerg; Ebner, Christian; Pfaltz, Andreas; Wennemers, Helma
Angewandte Chemie - International Edition, 2013 , vol. 52, # 48 p. 12619 - 12623
Angew. Chem., 2013 , p. 12851 - 12855,5
