甲基1,2,3,4-四-O-异丁酰基-beta-D-葡萄糖醛酸酯合成路线 （共 7 条）
反应条件
pyridine in dichloromethane T=10 - 20°C;
参考文献
Galantos Pharma GmbH
Patent: EP1777222 A1, 2007 ;
Location in patent: Page/Page column 27-28 ;
反应条件
1: methanol; D-(+)-glucuronic acid-γ-lactone With acetic acid; triethylamine 2: isobutyryl chloride With pyridine in dichloromethane T=40°C;
参考文献
Iddon, Lisa; Bragg, Ryan A.; Harding, John R.; Stachulski, Andrew V.
Tetrahedron, 2010 , vol. 66, # 2 p. 537 - 541
反应条件
1: 3,5,6-trihydroxy-tetrahydro-furo[3,2-b]furan-2-one; methanol With triethylamine 2: With acetic acid in methanol 3: isobutyryl chloride With pyridine
参考文献
Stanford (nee Sinnott), Deborah; Stachulski, Andrew V.
Tetrahedron Letters, 2007 , vol. 48, # 13 p. 2361 - 2364
反应条件
1: methanol; D-glucurono-6,3-lactone With sodium methylate Methylation; 2: isobutyryl chloride in pyridine; dichloromethane T=0 - 20°C; Acylation;
参考文献
Brown, Richard T; Carter, Neil E; Mayalarp, Stephen P; Scheinmann, Feodor
Tetrahedron, 2000 , vol. 56, # 38 p. 7591 - 7594
参考文献
Brown, Richard T.; Carter, Neil E.; Lumbard, Keith W.; Scheinmann, Feodor
Tetrahedron Letters, 1995 , vol. 36, # 47 p. 8661 - 8664
反应条件
2: 49 percent / pyridine View Scheme
参考文献
Brown, Richard T.; Carter, Neil E.; Lumbard, Keith W.; Scheinmann, Feodor
Tetrahedron Letters, 1995 , vol. 36, # 47 p. 8661 - 8664
反应条件
1: 73 percent / H2O, ammonia / CH2Cl2 2: 85 percent / anhyd. Na2CO3 View Scheme
参考文献
Brown, Richard T.; Carter, Neil E.; Lumbard, Keith W.; Scheinmann, Feodor
Tetrahedron Letters, 1995 , vol. 36, # 47 p. 8661 - 8664
