反应条件
1: 2) trimethylamine N-oxide / 1) CH2Cl2 2: H2 / Pd/C / ethyl acetate / 760 Torr 3: 95 percent / FeCl3, EtMgBr / diethyl ether; tetrahydrofuran / Ambient temperature 4: 1) O3, 2) Me2S 5: 90 percent 6: 72 percent / tetrahydrofuran / 0 °C 7: CF3COOH / CH2Cl2 / Ambient temperature 8: PDC / dimethylformamide / Ambient temperature 10: LiOH / methanol; H2O / Ambient temperature 11: Li, NH3 / tetrahydrofuran / -78 °C View Scheme
参考文献
Yoo, Sung-eun; Lee, Sang-Hee; Jeong, Nakcheol; Cho, Inho
Tetrahedron Letters, 1993 , vol. 34, # 21 p. 3435 - 3438