5-(2-甲氧基苯氧基)-[2,2'-二嘧啶]-4,6(1H,5H)-二酮合成路线 (共 3 条)
反应条件
1: 2-cyanopyrimidine With sodium methylate in methanol T=25 - 30°C; 3 h; 2: With ammonium chloride in methanol T=25 - 30°C; 3 h; 3: (2-methoxyphenoxy)-malonic acid dimethyl ester
参考文献
US2012/136015 A1, ;
Page/Page column 6-7 ;
反应条件
ethanol; sodium 16 h; Heating / reflux;
参考文献
AUSPEX PHARMACEUTICALS, INC.
Patent: US2008/242687 A1, 2008 ;
Location in patent: Page/Page column 32; 34 ;
US 20080242687 A1
反应条件
trichlorophosphate 4 h; Reflux;
参考文献
US2012/136015 A1, ;
Page/Page column 7 ;