乙基4-[8-甲氧基-4-[(2-甲基苯基)氨基]喹啉-3-基]-4-氧代丁酸酯合成路线 （共 3 条）
反应条件
in tetrahydrofuran T=60°C; Yield given;
参考文献
Pfizer Inc.
Patent: US5362743 A1, 1994 ;
反应条件
1: 82 percent / 3 h / 140 °C 2: 45 percent / diphenyl ether / 4 h / Heating 3: 36 percent / POCl3 / 1.5 h / Heating 4: tetrahydrofuran / 60 °C View Scheme
参考文献
Sarges, Reinhard; Gallagher, Andrea; Chambers, Timothy J.; Yeh, Li-An
Journal of Medicinal Chemistry, 1993 , vol. 36, # 19 p. 2828 - 2830
反应条件
1: 82 percent / 3 h / 140 °C 2: 45 percent / diphenyl ether / 4 h / Heating 3: 36 percent / POCl3 / 1.5 h / Heating 4: tetrahydrofuran / 60 °C View Scheme
参考文献
Sarges, Reinhard; Gallagher, Andrea; Chambers, Timothy J.; Yeh, Li-An
Journal of Medicinal Chemistry, 1993 , vol. 36, # 19 p. 2828 - 2830
