sodium hydroxide in water

1: With sodium hydroxide in methanol; water Heating; 2: With hydrogenchloride in methanol; water T=20°C;

1.1: anhydrous xylene / 1 h / Reflux 2.1: palladium 10 on activated carbon; hydrogen / methanol / 4 h / 2844.39 Torr 3.1: triethylamine / dichloromethane / 4 h / 20 °C 4.1: sodium hydroxide / methanol; water / Heating 4.2: 20 °C View Scheme

1.1: sodium / methanol / 12 h / -20 - 0 °C 2.1: anhydrous xylene / 1 h / Reflux 3.1: palladium 10 on activated carbon; hydrogen / methanol / 4 h / 2844.39 Torr 4.1: triethylamine / dichloromethane / 4 h / 20 °C 5.1: sodium hydroxide / methanol; water / Heating 5.2: 20 °C View Scheme

1.1: palladium 10 on activated carbon; hydrogen / methanol / 4 h / 2844.39 Torr 2.1: triethylamine / dichloromethane / 4 h / 20 °C 3.1: sodium hydroxide / methanol; water / Heating 3.2: 20 °C View Scheme