1: 60 percent / 1.) 4N KOH, 2.) 10percent HCl / H2O; methanol / 2 h / 70 °C 2: 87 percent / 1.) 60percent NaH, 2.) conc. HCl / dimethylformamide / 0 deg C to RT, 1 h 3: 78 percent / trifluoroacetic anhydride / CH2Cl2 / 2 h / Heating View Scheme

1: 87 percent / 1.) 60percent NaH, 2.) conc. HCl / dimethylformamide / 0 deg C to RT, 1 h 2: 78 percent / trifluoroacetic anhydride / CH2Cl2 / 2 h / Heating View Scheme