4-溴-2-(3-甲基丁-2-烯基)苯酚合成路线 （共 5 条）
反应条件
1: 4-bromo-phenol With sodium in diethyl ether Metallation; 2: prenyl bromide With zinc dibromide in dichloromethane Alkylation;
参考文献
Li, Yuan-Qiang; Sugase, Kenji; Ishiguro, Masaji
Tetrahedron Letters, 1999 , vol. 40, # 51 p. 9097 - 9100
反应条件
boron trifluoride diethyl etherate in 1,4-dioxane T=20°C; 72 h;
参考文献
Helesbeux, Jean-Jacques; Duval, Olivier; Guilet, David; Seraphin, Denis; Rondeau, David; Richomme, Pascal
Tetrahedron, 2003 , vol. 59, # 27 p. 5091 - 5104
反应条件
1: 78 percent / Et3N, DMAP / CH2Cl2
2: 60 percent / (o-tol)3P, Et3N / Pd(OAc)2 / toluene / 24 h / 100 °C
3: 89 percent / K2CO3 / methanol
View Scheme
参考文献
Bates; Gabel
Tetrahedron Letters, 1993 , vol. 34, # 22 p. 3547 - 3550
反应条件
1: With ArgoGelR-NH2-supported arylselenyl bromide in water
T=20°C;
2: With dihydrogen peroxide in water
T=20°C;
参考文献
Fujita, Ken-Ichi; Hashimoto, Shigeru; Oishi, Akihiro; Taguchi, Yoichi
Tetrahedron Letters, 2003 , vol. 44, # 19 p. 3793 - 3795
反应条件
1: 93 percent / K2CO3 / acetone / Heating
2: 85 percent / t-BuLi / tetrahydrofuran / -78 °C
View Scheme
参考文献
Li, Yuan-Qiang; Sugase, Kenji; Ishiguro, Masaji
Tetrahedron Letters, 1999 , vol. 40, # 51 p. 9097 - 9100
