2-(2-硝基苯基)乙醇合成路线 （共 40 条）
反应条件
sodium tetrahydroborate; CoCl2.6H2O; ethanol; diisopropylamine T=25 - 50°C; 24 h;
参考文献
COUNCIL OF SCIENTIFIC and INDUSTRIAL RESEARCH; RAWAT, Varun; BOOPATHI, Senthil, Kumar; ARUMUGAM, Sudalai
Patent: WO2013/140419 A1, 2013 ;
Location in patent: Page/Page column 32-33 ;
反应条件
sodium hydroxide in water; dimethyl sulfoxide T=50°C; 1 h; Large scale reaction;
参考文献
Guo, Xianghai; Peng, Zhiliang; Jiang, Shende; Shen, Jiaxiang
Synthetic Communications, 2011 , vol. 41, # 14 p. 2044 - 2052
反应条件
borane-THF in tetrahydrofuran Ambient temperature;
参考文献
Yamashita, Hiroshi; Amano, Koji; Shimada, Satoru; Narasaka, Koichi
Chemistry Letters, 1996 , # 7 p. 537 - 538
反应条件
potassium hydroxide; paraformaldehyde in water
参考文献
Reanal Finomvegyszergyar; Budapesti Muszaki Egyetem
Patent: US4299992 A1, 1981 ;
反应条件
potassium hydroxide; paraformaldehyde in dimethyl sulfoxide; ethyl acetate; Nalco silica sol 1060; toluene
参考文献
Pfleiderer; Wolfgang
Patent: US5763599 A1, 1998 ;
反应条件
sodium hydroxide; sodium tetrahydroborate in tetrahydrofuran; ethanol; water 1.) 5 deg C 2.) 2 h Room temperature;
参考文献
Wierenga, Wendell; Harrison, Allen W.; Evans, Bruce R.; Chidester, Connie G.
Journal of Organic Chemistry, 1984 , vol. 49, # 3 p. 438 - 442
反应条件
1: 95 percent / Br2; AlCl3 / diethyl ether 2: 56 percent / NaBH4; NaOH / ethanol; tetrahydrofuran; H2O / 1.) 5 deg C 2.) 2 h Room temperature View Scheme
参考文献
Journal of Organic Chemistry, , vol. 49, # 3 p. 438 - 442
反应条件
potassium hydroxide; 18-crown-6 ether in 1,4-dioxane 48 h; Ambient temperature; Yield given;
参考文献
Journal of Organic Chemistry, , vol. 49, # 3 p. 438 - 442
反应条件
1: 78 percent / NaOH / H2O 2: KOH / 18-crown-6 / dioxane / 48 h / Ambient temperature View Scheme
参考文献
Journal of Organic Chemistry, , vol. 49, # 3 p. 438 - 442
