2-(2-硝基苯基)乙醇合成路线 （共 40 条）
反应条件
1: 10 g / triethylamine; DBU / CH2Cl2 / 1 h / 20 °C 2: 1.0 g / zinc; acetic acid / 0.17 h View Scheme
参考文献
Subramanyam; Noguchi; Weinreb
Journal of Organic Chemistry, 1989 , vol. 54, # 23 p. 5580 - 5585
反应条件
1: 78 percent / calcium chloride; zinc powder / H2O / 0.5 h / Heating 2: 72 percent / NaHCO3 / dioxane View Scheme
参考文献
Minin, Patricia L.; Walton, John C.
Journal of Organic Chemistry, 2003 , vol. 68, # 7 p. 2960 - 2963
反应条件
1: 82 percent / pyridine / 3 h / 20 °C 2: 86 percent / 1-methyl-pyrrolidin-2-one / 1 h / 90 - 100 °C 3: 100 percent / aqueous sulfuric acid / 4.5 h / 130 - 135 °C 4: 61 percent / triphenylphosphine; diethyl azodicarboxylate / tetrahydrofuran / 16 h / 20 °C 5: hydrogen / Pd/C / methanol / atmospheric pressure 6: aq. phosphate buffer / 37 °C / pH 7.4 View Scheme
参考文献
Liu, Bin; Hu, Longqin
Bioorganic and Medicinal Chemistry, 2003 , vol. 11, # 18 p. 3889 - 3899
参考文献
Du, Peng; Peters, Dennis G.
Journal of the Electrochemical Society, 2010 , vol. 157, # 11 p. F167-F172
反应条件
1.1: pyridinium chlorochromate / dichloromethane / 3 h / 20 °C 2.1: dichloromethane / 3 h / -10 - 25 °C / Inert atmosphere 2.2: 24 h / 20 °C View Scheme
参考文献
Moreira, Nayara Da Rocha F.; De Oliveira, Tania T.; Nagem, Tanus J.; Taylor, Jason G.
Heterocyclic Communications, 2011 , vol. 17, # 5-6 p. 203 - 205
参考文献
Reanal Finomvegyszergyar; Budapesti Muszaki Egyetem
Patent: US4299992 A1, 1981 ;
反应条件
1: pyridinium chlorochromate / dichloromethane / 3 h / 20 °C 2: dichloromethane / 3 h / -10 - 25 °C / Inert atmosphere View Scheme
参考文献
Moreira, Nayara Da Rocha F.; De Oliveira, Tania T.; Nagem, Tanus J.; Taylor, Jason G.
Heterocyclic Communications, 2011 , vol. 17, # 5-6 p. 203 - 205
反应条件
4-(N,N-dimethlyamino)pyridine; trifluoromethylsulfonic anhydride; ammonia 1.) CH2Cl2, from -30 deg C to RT, 2.) THF, from -30 deg C to RT; Multistep reaction;
参考文献
Muchowski,J.M.
Canadian Journal of Chemistry, 1971 , vol. 49, p. 2023 - 2028
反应条件
dimethyl amine in ethanol
参考文献
Laboratoires Sarget
Patent: US4333930 A1, 1982 ;
反应条件
pyridinium chlorochromate in dichloromethane T=25°C; 6 h;
参考文献
COUNCIL OF SCIENTIFIC and INDUSTRIAL RESEARCH; RAWAT, Varun; BOOPATHI, Senthil, Kumar; ARUMUGAM, Sudalai
Patent: WO2013/140419 A1, 2013 ;
Location in patent: Page/Page column 23-24 ;
