反应条件
1: diethyl 2-acetylaminomalonate With sodium hydride in N,N-dimethyl-formamide T=20°C; 5 h; 2: α-bromoacetophenone in N,N-dimethyl-formamide T=20°C; 15 h; Further stages.;
参考文献
Camacho, Encarnacion; Leon, Josefa; Carrion, Adoracion; Entrena, Antonio; Escames, Germaine; Khaldy, Huda; Acuna-Castroviejo, Dario; Gallo, Miguel A.; Espinosa, Antonio
Journal of Medicinal Chemistry, 2002 , vol. 45, # 2 p. 263 - 274
