4-羟基-3-碘苯甲酸甲酯合成路线 (共 32 条)
反应条件
iodine cloride in acetic acid T=20 - 65°C; 21.6667 h;
参考文献
CYTOKINETICS, INC.; SMITHKLINE BEECHAM CORPORATION
Patent: WO2005/107762 A2, 2005 ;
Location in patent: Page/Page column 253-254 ;
反应条件
sulfuric acid T=20 - 55°C; 20 h;
参考文献
THE CLEVELAND CLINIC FOUNDATION; ATTALA, Mohamed Naguib; BROWN, David L.
Patent: WO2014/11949 A2, 2014 ;
Location in patent: Page/Page column 0077 ;
反应条件
iodine cloride in chloroform; acetic acid
参考文献
THE WELLCOME FOUNDATION LIMITED
Patent: EP728018 B1, 2003 ;
反应条件
sodium hydrogen telluride; acetic acid in ethanol 4 h; Heating;
参考文献
Vasil'ev, Andrei A.; Engman, Lars
Journal of Organic Chemistry, 1998 , vol. 63, # 12 p. 3911 - 3917
反应条件
sodium hydrogen telluride; acetic acid in ethanol 4 h; Heating; Yields of byproduct given;
参考文献
Vasil'ev, Andrei A.; Engman, Lars
Journal of Organic Chemistry, 1998 , vol. 63, # 12 p. 3911 - 3917
反应条件
chloramine-T; sodium iodide in acetonitrile T=20°C; 1.5 h;
参考文献
Synthesis, , # 6 art. no. Z01205SS, p. 1019 - 1027
反应条件
sodium tetrahydroborate; acetic acid in ethanol
参考文献
Journal of Organic Chemistry, , vol. 63, # 12 p. 3911 - 3917
反应条件
1: NaNO2, HCl, KI 2: CH2Cl2; methanol View Scheme
参考文献
Tetrahedron Letters, , vol. 39, # 16 p. 2281 - 2284
反应条件
1: NaClO; aqueous NaOH; KI 2: H2SO4 View Scheme
参考文献
Farmaco, Edizione Scientifica, , vol. 13, p. 121,123
反应条件
in methanol; dichloromethane
参考文献
Tetrahedron Letters, , vol. 39, # 16 p. 2281 - 2284