4-羟基-3-碘苯甲酸甲酯合成路线 （共 32 条）
反应条件
sodium carbonate in N,N-dimethyl-formamide T=95°C;
参考文献
Sperry, Jeffrey B.; Sutherland, Karen
Organic Process Research and Development, 2011 , vol. 15, # 3 p. 721 - 725
反应条件
1.1: sodium hydride / N,N-dimethyl-formamide / 1 h / 0 °C
1.2: 4 h / 20 °C
2.1: tetrabutyl-ammonium chloride; sodium formate; sodium carbonate / palladium diacetate / N,N-dimethyl-formamide / 2 h / 80 °C
3.1: sodium hydroxide; water / methanol / 20 °C
3.2: pH 5
View Scheme
参考文献
BIOENERGENIX
Patent: US2012/277224 A1, 2012 ;
US 20120277224 A1
