2,6-二氟吡啶合成路线

参考文献

Inorganic Chemistry, , vol. 48, # 3 p. 1030 - 1037

1513-65-12,6-二氟吡啶+

75-05-8乙腈

312325-71-62-(6-氟吡啶-2-基)乙腈

参考文献

Skerlj; Bogucki; Bridger
Synlett, 2000 , # 10 p. 1488 - 1490

1513-65-12,6-二氟吡啶+

73183-34-3联硼酸频那醇酯

1204333-58-32,6-二氟吡啶-4-硼酸频哪醇酯

参考文献

GLAXO GROUP LIMITED; ALDER, Catherine Mary; BALDWIN, Ian Robert; BARTON, Nicholas Paul; CAMPBELL, Amanda Jennifer; CHAMPIGNY, Aurelie Cecile; HARLING, John David; MAXWELL, Aoife Caitriona; SIMPSON, Juliet Kay; SMITH, Ian Edward David; TAME, Christopher John; WILSON, Caroline; WOOLVEN, James Michael
Patent: WO2011/110575 A1, 2011 ;
Location in patent: Page/Page column 74-75 ;
WO 2011/110575 A1

1513-65-12,6-二氟吡啶+

691-64-5二叔丁基草酸酯

155601-70-02-(2,6-二氟-3-吡啶基)-2-氧乙酸叔丁酯

参考文献

LEXICON PHARMACEUTICALS, INC.
Patent: WO2008/67121 A2, 2008 ;
Location in patent: Page/Page column 76 ;

1513-65-12,6-二氟吡啶

155601-70-02-(2,6-二氟-3-吡啶基)-2-氧乙酸叔丁酯

参考文献

Shutske, Gregory M.; Roehr, Joachim E.
Journal of Heterocyclic Chemistry, 1997 , vol. 34, # 3 p. 789 - 795

1513-65-12,6-二氟吡啶

155601-71-16-氟-1H-吡唑并[3,4-b]吡啶-3-羧酸叔丁酯

参考文献

Shutske, Gregory M.; Roehr, Joachim E.
Journal of Heterocyclic Chemistry, 1997 , vol. 34, # 3 p. 789 - 795

1513-65-12,6-二氟吡啶

1597-32-62-氨基-6-氟吡啶

参考文献

SMITHKLINE BEECHAM CORPORATION
Patent: WO2006/36816 A2, 2006 ;
Location in patent: Page/Page column 59-60 ;
WO 2006/036816 A2

2591-86-8哌啶-1-甲醛+

1513-65-12,6-二氟吡啶

155601-65-32,6-二氟吡啶-3-甲醛

参考文献

ANORMED INC.
Patent: WO2007/22371 A2, 2007 ;
Location in patent: Page/Page column 61 ;
WO 2007/022371 A2

1513-65-12,6-二氟吡啶+

68-12-2N,N-二甲基甲酰胺

155601-65-32,6-二氟吡啶-3-甲醛

参考文献

Schlosser, Manfred; Rausis, Thierry
European Journal of Organic Chemistry, 2004 , # 5 p. 1018 - 1024

1513-65-12,6-二氟吡啶+

67242-59-5N-甲基-N-(2-吡啶)甲酰胺

155601-65-32,6-二氟吡啶-3-甲醛

参考文献

Shutske, Gregory M.; Roehr, Joachim E.
Journal of Heterocyclic Chemistry, 1997 , vol. 34, # 3 p. 789 - 795