3,4-dihydroxy-1-tert-butylbenzene; lithium chloride; tetrakis(triphenylphosphine) palladium(0) in 1,4-dioxane 4 h; Heating; Yield given;

palladium diacetate; 1,3-bis-(diphenylphosphino)propane; triethylamine in dimethyl sulfoxide T=70°C; 5 h;

1: copper(l) iodide; tetrakis(triphenylphosphine) palladium(0); triphenylphosphine; piperidine / |Molecular sieve; |Inert atmosphere; |Reflux 2: sodium hydroxide / tetrahydrofuran; water / 2 h / 20 °C View Scheme

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '105690', constants.ctx, '0')">2,6-dimethylpyridine</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '110354', constants.ctx, '0')">4-(N,N-dimethlyamino)pyridine</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '102391', constants.ctx, '0')">tetrahydrofuran</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '1730800', constants.ctx, '0')">dichloromethane</a> <br />T=-78 - 0&deg;C;&nbsp;<br /> &nbsp;

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '110354', constants.ctx, '0')">4-(N,N-dimethlyamino)pyridine</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '5814770', constants.ctx, '0')">trifluoromethanesulfonic acid anhydride</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '102391', constants.ctx, '0')">tetrahydrofuran</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '1730800', constants.ctx, '0')">dichloromethane</a> <br /> <br /> <br /> &nbsp;

&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '103233', constants.ctx, '0')">pyridine</a> <br />T=20&deg;C;&nbsp;16&nbsp;h;&nbsp;<br /> &nbsp;