2-氯-2,2-二氟乙酸甲酯合成路线 （共 95 条）
反应条件
potassium fluoride; copper(l) iodide in N,N-dimethyl-formamide T=120°C; 8 h; other methyl halodifluoroacetates, var. organic halides, var. temp., var. time; Product distribution;
参考文献
Journal of Fluorine Chemistry, , vol. 61, # 3 p. 279 - 284
反应条件
potassium fluoride; copper(l) iodide in N,N-dimethyl-formamide T=100 - 120°C; 8 h; other solvent; other organic halides; Product distributionMechanism;
参考文献
Tetrahedron Letters, , vol. 32, # 52 p. 7689 - 7690
反应条件
potassium fluoride; copper(l) iodide in N,N-dimethyl-formamide T=120°C; 8 h; also with bromobenzene; further times and temperatures for methyl bromodifluoroacetates; Product distributionMechanism;
参考文献
Journal of Fluorine Chemistry, , vol. 65, # 1-2 p. 11 - 14
反应条件
caesium carbonate in N,N-dimethyl-formamide T=65°C; 3 h; Inert atmosphere;
参考文献
Journal of Medicinal Chemistry, , vol. 51, # 24 p. 7673 - 7688
反应条件
caesium carbonate in N,N-dimethyl-formamide
参考文献
Bioorganic and medicinal chemistry letters, , vol. 12, # 11 p. 1457 - 1461
反应条件
caesium carbonate in N,N-dimethyl-formamide
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 12, # 16 p. 2149 - 2152
反应条件
N,N'-dimethyl-N,N'-propyleneurea; potassium fluoride; copper(l) iodide heating;
参考文献
MacNeil, James G.; Burton, Donald J.
Journal of Fluorine Chemistry, 1991 , vol. 55, # 2 p. 225 - 228
反应条件
potassium fluoride; copper(l) iodide in N,N-dimethyl-formamide T=120°C; 8 h; also with bromobenzene; further times and temperatures for methyl bromodifluoroacetates; Product distributionMechanism;
参考文献
Su, De-Bao; Duan, Jian-Xing; Yu, An-Juan; Chen, Qing-Yun
Journal of Fluorine Chemistry, 1993 , vol. 65, # 1-2 p. 11 - 14
反应条件
potassium carbonate in ethyl acetate; N,N-dimethyl-formamide
参考文献
SmithKline Beecham Corporation
Patent: US5731477 A1, 1998 ;
反应条件
potassium fluoride; copper(l) iodide; iodine in N,N-dimethyl-formamide T=120°C; 3 h;
参考文献
Journal of the Chemical Society - Series Chemical Communications, , # 11 p. 807 - 808
