4-异丙基-1H-吡唑-3-胺合成路线 （共 3 条）
反应条件
1: With acetic acid; hydrazine in ethanol 16 h; Heating / reflux; 2: With sodium hydrogencarbonate in ethanol; water
参考文献
VERNALIS (CAMBRIDGE) LIMITED
Patent: WO2004/87707 A1, 2004 ;
Location in patent: Page 27; 28 ;
WO 2004/087707 A1
反应条件
ammonia; sodium amide 1.) 5 min, 2.) 1 h; Multistep reaction;
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 46, # 1 p. 69 - 78
反应条件
1.1: ethanol; sodium / 16 h / Reflux
1.2: pH 3
2.1: trichlorophosphate; N,N-dimethyl-aniline / 16 h / Reflux
View Scheme
参考文献
Liotta, Dennis C.; Snyder, James P.; Jogalekar, Ashutosh S.; Barrett, Anthony G.M.; Fuchter, Matthew John; Cook, Matthew J.; Kroll, Sebastian H.B.
Patent: US2012/41198 A1, 2012 ;
US 20120041198 A1
