4,7-二溴-2,1,3-苯并噻二唑合成路线 （共 42 条）
反应条件
cesium fluoride in 1,4-dioxane
Suzuki coupling reaction;
参考文献
DaSilveira Neto, Brenno A.; Lopes, Aline S.; Wuest, Martina; Costa, Valentim E. U.; Ebeling, Guenter; Dupont, Jairton
Tetrahedron Letters, 2005 , vol. 46, # 40 p. 6843 - 6846
反应条件
1: 94 percent / CsF / NCP-pincer palladacycle / dioxane / 18 h / 130 °C
2: 82 percent / NaBH4; CoCl2*6H2O / ethanol
View Scheme
参考文献
DaSilveira Neto, Brenno A.; Lopes, Aline S.; Wuest, Martina; Costa, Valentim E. U.; Ebeling, Guenter; Dupont, Jairton
Tetrahedron Letters, 2005 , vol. 46, # 40 p. 6843 - 6846
反应条件
cesium fluoride; NCP-pincer palladacycle in 1,4-dioxane
T=130°C; Suzuki coupling reaction; 18 h;
参考文献
Mancilha, Fabiana S.; DaSilveira Neto, Brenno A.; Lopes, Aline S.; Moreira Jr., Paulo F.; Quina, Frank H.; Goncalves, Reinaldo S.; Dupont, Jairton
European Journal of Organic Chemistry, 2006 , # 21 p. 4924 - 4933
反应条件
1: 92 percent / CsF / NCP-pincer palladacycle / dioxane / 18 h / 130 °C
2: 94 percent / NaBH4; CoCl2*6H2O / ethanol
View Scheme
参考文献
Mancilha, Fabiana S.; DaSilveira Neto, Brenno A.; Lopes, Aline S.; Moreira Jr., Paulo F.; Quina, Frank H.; Goncalves, Reinaldo S.; Dupont, Jairton
European Journal of Organic Chemistry, 2006 , # 21 p. 4924 - 4933
反应条件
sodium tetrahydroborate; cobalt(II) chloride in ethanol
3 h; Heating;
参考文献
DaSilveira Neto, Brenno A.; Lopes, Aline S.; Wuest, Martina; Costa, Valentim E. U.; Ebeling, Guenter; Dupont, Jairton
Tetrahedron Letters, 2005 , vol. 46, # 40 p. 6843 - 6846
反应条件
acetic acid; zinc in water
参考文献
HITACHI CHEMICAL CO. LTD.; MAXDEM INCORPORATED
Patent: US2006/83945 A1, 2006 ;
反应条件
1: 87 percent / NaBH4 / ethanol / 20 h / 0 - 20 °C
2: 70 percent / ethanol / 1 h / Heating
View Scheme
参考文献
INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
Patent: US2012/305901 A1, 2012 ;
反应条件
copper(l) iodide; triethylamine; triphenylphosphine; bis-triphenylphosphine-palladium(II) chloride
T=90°C; Sonogashira coupling; 72 h;
参考文献
Neto, Brenno A. D.; Lapis, Alexandre A. M.; Mancilha, Fabiana S.; Vasconcelos, Igor B.; Thum, Caroline; Basso, Luiz A.; Santos, Diogenes S.; Dupont, Jairton
Organic Letters, 2007 , vol. 9, # 20 p. 4001 - 4004
反应条件
bis-triphenylphosphine-palladium(II) chloride; triethylamine; copper(I) bromide
T=90°C; Sonogashira cross-coupling reaction; 48 h;
参考文献
Akhtaruzzaman; Tomura, Masaaki; Zaman, Md. Badruz; Nishida, Jun-ichi; Yamashita, Yoshiro
Journal of Organic Chemistry, 2002 , vol. 67, # 22 p. 7813 - 7818
反应条件
cesium fluoride; NCP-pincer palladacycle in 1,4-dioxane
T=130°C; 18 h;
参考文献
Mancilha, Fabiana S.; DaSilveira Neto, Brenno A.; Lopes, Aline S.; Moreira Jr., Paulo F.; Quina, Frank H.; Goncalves, Reinaldo S.; Dupont, Jairton
European Journal of Organic Chemistry, 2006 , # 21 p. 4924 - 4933
